Fournier’s gangrene: A retrospective analysis of 26 cases in a Canadian hospital and literature

Authors

  • Michael McCormack University of Montreal
  • Anne Sophie Valiquette University of Montreal
  • Salima Ismail University of Montreal

DOI:

https://doi.org/10.5489/cuaj.2445

Abstract

We performed a systematic review of all cases of Fournier’s Gangrene (FG) at our hospital over a 12-year period. A total of 26 cases were assessed. Our goal was to determine the mortality rate and to identify risk factors associated with FG. We also wanted to examine three potential prognostic factors in relation to patient survival, including the time delay from emergency room admission to surgery, the initial extent of the disease, and the impact of more than one debridement procedure under general anesthesia. The time between emergency room admission and the beginning of surgical debridement was not statistically different between survivors and non-survivors. The extent of surgical debridement was close to the margin of statistical significance (p = 0.07) and can be considered an index of the extent of the disease. FG extending to the thighs or to the abdominal wall carries a worse prognosis. The number of surgical debridement procedures done under anesthesia was statistically different between survivors and nonsurvivors. Patients were 4.8 times more at risk of dying if they are required to have more than one surgical debridement under general anesthesia. This presumably reflects persistent gangrene following initial surgical debridement, fluid resuscitation, and wide spectrum antibiotic treatment.

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Author Biographies

Michael McCormack, University of Montreal

Assistant Professor of Surgery

Departement of Surgery

University of Montreal

Anne Sophie Valiquette, University of Montreal

Resident

Departement of Surgery

University of Montreal

 

Salima Ismail, University of Montreal

Resident

Departement of Surgery

University of Montreal

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Published

2015-06-18

How to Cite

McCormack, M., Valiquette, A. S., & Ismail, S. (2015). Fournier’s gangrene: A retrospective analysis of 26 cases in a Canadian hospital and literature. Canadian Urological Association Journal, 9(5-6), E407–10. https://doi.org/10.5489/cuaj.2445

Issue

Vol. 9 No. 5-6 (2015): CUAJ June

Section

Review

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