The association between the anatomical features of renal tumours and the functional outcomes of robot-assisted partial nephrectomy

Authors

  • Jeong Woo Lee Department of Urology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
  • Sung Yong Cho Department of Urology, SMG-SNU Boramae Medical center, Seoul, Korea.
  • Chanhoo Jeon Department of Urology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Kyungtae Ko Department of Urology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Hyeon Hoe Kim Department of Urology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

DOI:

https://doi.org/10.5489/cuaj.1642

Keywords:

Robot-assisted partial nephrectomy, renal tumor, ischemic time, renal function

Abstract

Introduction: We evaluated the the association between PADUA scores and postoperative renal function (after robot-assisted partial nephrectomy [RAPN]) and between PADUA scores and warm ischemic time (during RAPN).

Methods: We reviewed the clinical records of 106 patients who underwent RAPN for a single localized renal tumour between April 2009 and June 2012. Postoperative renal function was evaluated using estimated glomerular filtration rate (eGFR) in 85 patients who were followed for at least 6 months. PADUA scores for renal tumours were calculated using contrast-enhanced computed tomography images, if needed, along with magnetic resonance images in some cases.

Results: A PADUA score ≥10 and WIT ≥30 minutes were observed in 18 (17.0%) and 51 (48.1%) cases, respectively. PADUA scores were significantly correlated with WIT (p = 0.019) and percent change in eGFR at 6 months postoperatively (p = 0.005). PADUA score (continuous variable, odds ratio [OR] 1.694, p = 0.007) and the high-risk group (PADUA score ≥10) (OR 5.429; p = 0.020) were significantly associated with a WIT of ≥30 minutes by multivariate analysis. A 1-point increase in the PADUA score was associated with an eGFR decrease of >20% at 6 months after RAPN (OR 1.799; p = 0.076). In addition, a PADUA score ≥10, or high risk, (OR 13.965; p = 0.003) was an independent predictor of an eGFR decrease of >20% at 6 months after RAPN.

Conclusions: The PADUA classification can reliably predict WIT and postoperative renal functional outcome after RAPN. Furthermore, the study suggests that anatomical aspects of renal tumours are associated with functional outcome after RAPN.

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Published

2014-11-24

How to Cite

Lee, J. W., Cho, S. Y., Jeon, C., Ko, K., & Kim, H. H. (2014). The association between the anatomical features of renal tumours and the functional outcomes of robot-assisted partial nephrectomy. Canadian Urological Association Journal, 8(11-12), e810–4. https://doi.org/10.5489/cuaj.1642

Issue

Vol. 8 No. 11-12 (2014): CUAJ November

Section

Original Research

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