Strain elastography in the characterization of renal cell carcinoma and angiomyolipoma

Authors

  • Suat Keskin Necmettin Erbakan University, Meram School of Medicine
  • Selçuk Güven Department of Urology, Necmettin Erbakan University, Meram School of Medicine
  • Zeynep Keskin Department of Radiology, Konya Training and Research Hospital, Konya
  • Hüseyin Özbiner Department of Radiology, Necmettin Erbakan University, Meram School of Medicine
  • Ülkü Kerimoğlu Department of Radiology, Necmettin Erbakan University, Meram School of Medicine
  • Ahmet Yeşildağ Department of Radiology, Necmettin Erbakan University, Meram School of Medicine

DOI:

https://doi.org/10.5489/cuaj.2349

Keywords:

ultrasonography, elastography, strain, strain ratio, renal neoplasm

Abstract

Introduction: We evaluate the diagnostic performance of strain elastography to differentiate renal cell carcinoma (RCC) from angiomyolipoma (AML).

Methods: Strain elastography was performed in 65 patients (mean age 55.5 years; range: 32–81) who had renal lesions (24 AMLs and 41 RCCs) prospectively. Lesions were classified according to lesion size and histological subtypes. The strain ratios of the RCCs and AMLs were evaluated by a radiologist. The area under the curve and the cut-off point were used to assess diagnostic performance. Sensitivity, specificity, and positive and negative predictive values were obtained.

Results: In assessing the mean strain ratio, we divided the groups in 3 according to size: (1) <20-mm lesions; (2) 20- to 40-mm lesions; and (3) >40-mm lesions; the respective mean strain ratios were: 1.5 ± 0.5 (range: 0.06–5.92), 2.8 ± 0.4 (range: 0.17–9.92), 2.7 ± 0.3 (range: 0.08–6.15). When RCCs and AMLs were compared, there was a statistically significant difference in the strain ratio among the 3 groups divided per lesion size (p < 0.01). For the strain ratio, the mean ± standard deviation was 1.1 ± 0.1 for AMLs and 3.4 ± 0.3 for RCCs (p < 0.01). When lesion subtypes were compared, there was a statistically significant difference in the strain ratio between the AML and clear cell RCC (p < 0.01).

Conclusions: For assessing renal lesions, strain elastography and strain ratio values may be useful in differentiating RCCs from AMLs.

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Published

2015-02-09

How to Cite

Keskin, S., Güven, S., Keskin, Z., Özbiner, H., Kerimoğlu, Ülkü, & Yeşildağ, A. (2015). Strain elastography in the characterization of renal cell carcinoma and angiomyolipoma. Canadian Urological Association Journal, 9(1-2), e67–71. https://doi.org/10.5489/cuaj.2349

Issue

Section

Original Research