A case report of retroperitoneal Castleman disease
DOI:
https://doi.org/10.5489/cuaj.1099Abstract
Castleman disease (CD) is an uncommon lymphoproliferative disorderand is especially rare in the retroperitoneum or perirenal
area. We report the case of a 42-year-old woman in whom we found
on routine physical examination a mass localized in the right
abdomen without clinically important constitutional symptoms for
30 days. Abdominal ultrasound, magnetic resonance images and
computed tomography scans revealed a solid mass localized just
below the right kidney in the retroperitoneum. The patient subsequently
underwent an exploratory laparotomy. Pathological examination
revealed a right retroperitoneal mass of CD (hyaline vascular
type). The patient completely recovered after surgery. Castleman
disease is commonly misdiagnosed as malignant lymphoma,
lymphadenitis or ectopic thymoma. So far, its diagnosis is mainly
achieved via histopathological examination of surgically obtained
tissue. After removal of the lesion, local CD has a good prognosis.
La maladie de Castleman est un trouble lymphoprolifératif rare,
surtout dans les régions rétropéritonéale ou périrénale. Nous
décrivons le cas d'une femme de 42 ans chez qui un examen
physique de routine a révélé la présence d'une masse localisée
au côté droit de l'abdomen sans que cette patiente n'affiche de
symptômes constitutionnels d'importance clinique pendant 30 jours.
Des images obtenues par échographie abdominale, par IRM et par
tomodensitométrie ont révélé la présence d'une masse solide située
juste en dessous du rein droit dans la région rétropéritonéale. La
patiente a ensuite subi une laparotomie exploratoire. L'examen
d'histopathologie a révélé une masse rétropéritonéale droite caractéristique
de la maladie de Castleman dans sa forme hyaline vasculaire.
La patiente s'est complètement rétablie après l'intervention.
Au moment du diagnostic, la maladie de Castleman est souvent
confondue avec un lymphome malin, une lymphadénite ou un thymome
ectopique. Jusqu'à présent, le diagnostic de cette maladie
est posé principalement sur la base d'un examen histopathologique
de tissus prélevés par chirurgie. Après ablation de la masse, le
pronostic lié à la maladie de Castleman est favorable.
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