Prédicteurs de succès après épididymovasostomie bilatérale réalisée lors de l'inversion de vasectomie: une analyse multi-institutionnelle.

Auteurs-es

  • Jesse Ory Department of Urology, Dalhousie University
  • Sirpi Nackeeran
  • Udi Blankstein
  • Joshua T. White
  • Ethan Grober
  • Sheldon H. Marks
  • Ranjith Ramasamy

DOI :

https://doi.org/10.5489/cuaj.7441

Mots-clés :

infertility, vasectomy reversal, microsurgery, multi-institutional analysis, epididymovasostomy

Résumé

Introduction: Vasectomy reversal (VR) represents an excellent option for paternity in men who desire to expand their family following vasectomy. Traditional VR via vasovasostomy has a success rate upwards of 90%1,2 but when sperm or sperm parts are not present in vasal fluid, epididymovasostomy (EV) must be performed instead. Our objective was to determine which factors influence success after bilateral EV.

Methods: A prospectively maintained database with data from the U.S. and Canada was used to identify men who underwent bilateral EV at time of VR. Success was defined as motile sperm in any postoperative semen analyses. Multivariable logistic regression was used to identify predictors of success.

Results: A total of 200 men had at least one postoperative semen analysis, and 171 men were included in the analysis. Average age was 44.7 years, with average followup of seven months. Median time elapsed between vasectomy and EV was 15 years (interquartile range [IQR] 10–18). Overall success rate was 50%. Despite the study being adequately powered, factors such as years since vasectomy (odds ratio [OR] 1.01, confidence interval [CI] 0.95–1.06), age (OR 0.96, CI 0.91–1.01), intraoperative presence of motile sperm (OR 0.81, CI 0.41–1.62), and epidydimal fluid characteristics did not predict success.

Conclusions: Bilateral EV at time of VR is successful in 50% of cases in a multi-institutional, North American cohort. Microsurgeons can be reassured that neither time elapsed nor epididymal fluid characteristics negatively impact success rates as long as sperm or sperm parts are present. Surgeons performing VR should be comfortable and prepared to perform EV if indicated.

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Publié-e

2021-10-18

Comment citer

Ory, J., Nackeeran, S., Blankstein, U., White, J. T., Grober, E., Marks, S. H., & Ramasamy, R. (2021). Prédicteurs de succès après épididymovasostomie bilatérale réalisée lors de l’inversion de vasectomie: une analyse multi-institutionnelle. Canadian Urological Association Journal, 16(3), E132–6. https://doi.org/10.5489/cuaj.7441

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Original Research