Treatment options in advanced renal cell carcinoma after first-line treatment with vascular endothelial growth factor receptor tyrosine kinase inhibitors

Auteurs-es

  • Naveen S. Basappa

DOI :

https://doi.org/10.5489/cuaj.4292

Résumé

Targeted therapy for metastatic renal cell carcinoma (mRCC) was introduced a decade ago, and since then a number of therapeutic options have been developed. Vascular endothelial growth factor targeted therapy is the widely accepted first-line option for mRCC. After progression, treatment in the second-line setting has typically been with either axitinib or everolimus. However, with the advent of several new agents demonstrating efficacy in the second-line setting, including nivolumab, cabozantinib, and the combination of lenvatinib and everolimus, the treatment paradigm has shifted toward these novel therapies with improved patient outcomes.

Téléchargements

Les données relatives au téléchargement ne sont pas encore disponibles.

Téléchargements

Publié-e

2016-12-15

Comment citer

Basappa, N. S. (2016). Treatment options in advanced renal cell carcinoma after first-line treatment with vascular endothelial growth factor receptor tyrosine kinase inhibitors. Canadian Urological Association Journal, 10(11-12), S242–4. https://doi.org/10.5489/cuaj.4292

Numéro

Rubrique

Supplement-Review