Urothelial-based reconstructive surgery for upper- and mid-ureteral defects: Long-term results

Auteurs-es

  • Barak Rosenzweig Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel The Dr. Pinchas Borenstein Talpiot Medical Leadership Program 2013 The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
  • Yoram Mor Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • Tomer Erlich Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • Menachem Laufer Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • Harry Winkler Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • Issac Kaver Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • Jacob Ramon Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • Zohar A. Dotan Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel

DOI :

https://doi.org/10.5489/cuaj.3659

Résumé

Introduction: Ureteral strictures can result in obstructive nephropathy and renal function deterioration. Surgical management of ureteral defects, especially in the proximal- and mid-ureter, is particularly challenging. Our purpose was to analyze the long-term outcomes of urothelial-based reconstructive surgery for upper- and mid-ureteral defects.

Methods: We conducted a retrospective analysis of a single tertiary centre’s database, including 149 patients treated for ureteral defects between 2001 and 2011. Thirty-one patients (21%) underwent complex urothelial-based surgical repairs for upper- and mid-ureter defects. Patients’ median age was 61 years. The mean length of the ureteral strictures was 2.5 cm, located in upper-, mid-ureter, or in between in 19 (61%), 10 (32%), and two (6%) patients, respectively. All patients were treated with a primary urothelial-based repair. Median followup time was 26 months. The primary outcome of the study was the long-term preservation of renal function and lack of clinical obstruction. The secondary endpoint of the study was the assessment of the intra- and postoperative complication rates.

Results: Most of the lesions were benign (22, 71%), while nine strictures (29%) were malignant. Seven patients (23%) suffered from postoperative complications, five of which were infectious. The median pre- and postoperative calculated glomerular filtration rates were 66 ml/min/1.72m2 and 64ml/min/1.72m2, respectively. Success rate was 84%, defined as lack of need for re-operation or kidney drainage at the last followup.

Conclusions: Upper- and mid-ureteral defects present a complex pathology necessitating experienced reconstructive surgical skills. Our data suggest good long-term results for primary urothelialbased reconstructions for these pathologies.

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Biographie de l'auteur-e

Barak Rosenzweig, Department of Urology The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel The Dr. Pinchas Borenstein Talpiot Medical Leadership Program 2013 The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel

Urology resident

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Publié-e

2016-09-13

Comment citer

Rosenzweig, B., Mor, Y., Erlich, T., Laufer, M., Winkler, H., Kaver, I., … Dotan, Z. A. (2016). Urothelial-based reconstructive surgery for upper- and mid-ureteral defects: Long-term results. Canadian Urological Association Journal, 10(9-10), E290–5. https://doi.org/10.5489/cuaj.3659

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Rubrique

Original Research