Spontaneous regression of metastatic pulmonary renal cell carcinoma in the setting of sarcomatoid differentiation of the primary tumour

Authors

  • Brian PH Chan Queen’s University, Kingston, Ontario, Canada
  • Christopher M Booth Queen’s University, Kingston, Ontario, Canada
  • Marosh Manduch Queen’s University, Kingston, Ontario, Canada
  • Naji J Touma Queen’s University, Kingston, Ontario, Canada

DOI:

https://doi.org/10.5489/cuaj.169

Keywords:

Renal cell carcinoma, sarcomatoid, neoplasm metastases, spontaneous regression.

Abstract

We present a case of spontaneous regression of pulmonary metastases from renal cell carcinoma (RCC) with sarcomatoid differentiation, prior to intervention. The patient presented with conventional type RCC with Furhman Grade 4/4 and sarcomatoid differentiation, complicated by pulmonary metastases. Palliative systemic therapy was planned, but prior to the onset of treatment, serial computed tomography scans demonstrated regression of metastatic disease. Spontaneous regression of metastases is rare, but well-documented in conventional clear cell RCC. To the best of our knowledge, this has not previously been described in the setting of sarcomatoid differentiation of the primary tumour.

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Author Biographies

Brian PH Chan, Queen’s University, Kingston, Ontario, Canada

Medical Student, School of Medicine

Christopher M Booth, Queen’s University, Kingston, Ontario, Canada

Assistant Professor, Department of Oncology

Marosh Manduch, Queen’s University, Kingston, Ontario, Canada

Assistant Professor, Department of Pathology and Molecular Medicine

Naji J Touma, Queen’s University, Kingston, Ontario, Canada

Assistant Professor, Department of Urology

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Published

2013-09-10

How to Cite

Chan, B. P., Booth, C. M., Manduch, M., & Touma, N. J. (2013). Spontaneous regression of metastatic pulmonary renal cell carcinoma in the setting of sarcomatoid differentiation of the primary tumour. Canadian Urological Association Journal, 7(9-10), e587–9. https://doi.org/10.5489/cuaj.169

Issue

Vol. 7 No. 9-10 (2013): CUAJ September

Section

Case Report

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