Multidisciplinary treatment including systemic chemotherapy for a malignant phyllodes tumour of the prostate

Auteurs-es

  • Yasukiyo Murakami Kitasato University School of Medicine
  • Ken-ichi Tabata Kitasato University School of Medicine
  • Atsushi Sugita Kitasato University School of Medicine
  • Kohei Mochizuki Kitasato University School of Medicine
  • Ryota Maeyama Kitasato University School of Medicine
  • Miyoko Okazaki Kitasato University School of Medicine
  • Morihiro Nishi Kitasato University School of Medicine
  • Kazumasa Matsumoto Kitasato University School of Medicine
  • Tetsuo Fujita Kitasato University School of Medicine
  • Takefumi Satoh Kitasato University School of Medicine
  • Shi- Xu Jiang Kitasato University School of Medicine
  • Makoto Saegusa Kitasato University School of Medicine
  • Masatsugu Iwamura Kitasato University School of Medicine

DOI :

https://doi.org/10.5489/cuaj.1648

Mots-clés :

phyllodes tumor, prostate, chemotherapy

Résumé

A 22-year-old man was referred to our hospital with macroscopic hematuria and consistent anal pain. Magnetic resonance imaging revealed an enlarged prostate tumour invading the bladder and rectum. A biopsy revealed an unclassified spindle cell sarcoma. Subsequently, radical cystoprostatectomy and resection of the rectum were performed. A histopathological examination revealed a prostatic malignant phyllodes tumour with a negative surgical margin. However, a local recurrence was identified 2 months after surgery. Induction therapy included 4 cycles of systemic chemotherapy comprising etoposide with ifosfamide and cisplatin. Although a partial response was observed at the local site, lung metastasis developed. Second-line chemotherapy with ifosfamide and doxorubicin with radiotherapy to the pelvis was administered and led to complete regression; however, its efficacy was transient. Although additional chemotherapy was administered, the patient eventually died due to the rapidly growing, recurrent tumour.

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Bibliographies de l'auteur-e

Yasukiyo Murakami, Kitasato University School of Medicine

Department of Urology

Ken-ichi Tabata, Kitasato University School of Medicine

Department of Urology

Atsushi Sugita, Kitasato University School of Medicine

Department of Urology

Kohei Mochizuki, Kitasato University School of Medicine

Department of Urology

Ryota Maeyama, Kitasato University School of Medicine

Department of Urology

Miyoko Okazaki, Kitasato University School of Medicine

Department of Pharmacology

Morihiro Nishi, Kitasato University School of Medicine

Department of Urology

Kazumasa Matsumoto, Kitasato University School of Medicine

Department of Urology

Tetsuo Fujita, Kitasato University School of Medicine

Department of Urology

Takefumi Satoh, Kitasato University School of Medicine

Department of Urology

Shi- Xu Jiang, Kitasato University School of Medicine

Department of pathology

Makoto Saegusa, Kitasato University School of Medicine

Department of pathology

Masatsugu Iwamura, Kitasato University School of Medicine

Department of Urology

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Publié-e

2014-04-14

Comment citer

Murakami, Y., Tabata, K.- ichi, Sugita, A., Mochizuki, K., Maeyama, R., Okazaki, M., … Iwamura, M. (2014). Multidisciplinary treatment including systemic chemotherapy for a malignant phyllodes tumour of the prostate. Canadian Urological Association Journal, 8(3-4), e263–5. https://doi.org/10.5489/cuaj.1648

Numéro

Rubrique

Case Report