Genitourinary malignancy presenting as an ocular metastasis: A case report and review of the literature
DOI:
https://doi.org/10.5489/cuaj.163Abstract
Metastases to the eye or orbit as the initial presentation of genitourinary
malignancy are unusual and can be a diagnostic challenge.
We report an 81-year-old man who presented with pain and
proptosis in an eye that had been blind for 50 years. Radiologic
investigations identified a mass involving the left globe and orbit.
Histology of the enucleation specimen was consistent with a metastatic
poorly differentiated carcinoma suggestive of a prostate
primary. With the constellation of obstructive urinary symptoms,
an abnormal digital rectal examination, elevated prostate-specific
antigen and a positive bone scan, androgen deprivation therapy
was initiated for metastatic prostate cancer. After an initial response
to treatment, the patient’s disease progressed in a manner atypical
for prostate cancer. After describing our case, we review the
literature on ocular and orbital metastases and their relation to
genitourinary malignancies.
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