Development of large language model-generated multiple-choice questions and flashcards to enhance the Canadian undergraduate urology curriculum

Authors

  • Othmane Zekraoui Faculty of Medicine, Université de Montréal, Montreal, QC, Canada
  • Tiange Li
  • David-Dan Nguyen
  • Marie-Lyssa Lafontaine
  • Tomas Cordoba
  • Mahmoud Moustafa
  • Dawn L. MacLellan
  • Julien Letendre
  • Malek Meskawi
  • Garson Chan
  • Sarah Neu
  • Dean Elterman
  • Bilal Chughtai
  • Brendan Wallace
  • Naeem Bhojani

DOI:

https://doi.org/10.5489/cuaj.9845

Keywords:

Artificial Intelligence, Education, Benign Prostatic Hyperplasia (BPH), Urolithiasis

Abstract

Introduction: The Canadian Undergraduate Urology Curriculum (CanUUC) is a free, online curriculum that covers important topics in urology for medical students. While multiple-choice questions (MCQs) and flashcards are widely used for medical education, they can be resource-intensive and time-consuming to produce. Therefore, to strengthen the CanUUC with such tools, we developed a customized large language model (LLM)-enabled system to generate MCQs and flashcards from CanUUC material and evaluated the quality of its outputs.

Methods: We used OpenAI’s GPT-5 model and refined two system prompts to generate educational materials from two CanUUC topics (benign prostatic hyperplasia and urolithiasis). Six evaluators blinded to items’ origin were involved, and each item received two independent ratings for relevance, correctness, clarity, distractor quality, and suitability for education. Items with a mean score <3 on the suitability for education evaluation domain were excluded. Results were summarized descriptively.

Results: Ninety items, including 40 MCQs and 50 flashcards were generated. Among flashcards, 22% allowed >1 plausible answer. Across all independent ratings, the proportion of top scores (4–5) ranged from 85.5−90.5% across all domains. Overall, 86.1% of independent ratings judged items suitable for medical education. When averaging the suitability score at the item-level, 12 items (13%) had a score <3 and were excluded. Mandatory (8%) and optional (27%) adjustments were suggested to refine items’ clarity and correctness. From the initially generated items, 87% were included in the CanUUC.

Conclusions: Our customized system can produce curriculum-aligned MCQs and flashcards that meet item writing standards and are mostly suitable for medical education. Expert review is essential to identify flaws and improve quality before inclusion into the curriculum.

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Published

2026-10-19

How to Cite

Zekraoui, O., Li, T., Nguyen, D.-D., Lafontaine, M.-L., Cordoba, T., Moustafa, M., … Bhojani, N. (2026). Development of large language model-generated multiple-choice questions and flashcards to enhance the Canadian undergraduate urology curriculum. Canadian Urological Association Journal, 21(2). https://doi.org/10.5489/cuaj.9845

Issue

Section

Original Research