Can preoperative vitamin D level be a predictive factor for continence after radical prostatectomy?

Authors

  • Emre Şam University of Health Sciences Erzurum City Hospital
  • Emrullah Söğütdelen Bolu Abant Izzet Baysal Training and Research Hospital
  • Fatih Akka University of Health Sciences Erzurum City Hospital
  • Kamil Gökhan Şeker Liv Hospital Vadistanbul
  • Deniz Noyan Özlü Bitlis State Hospital
  • Ekrem Güner Dr. Sadi Konuk Training and Research Hospital

DOI:

https://doi.org/10.5489/cuaj.8999

Keywords:

Post-prostatectomy incontinence, Vitamin D, Robotic radical prostatectomy

Abstract

INTRODUCTION: This study examined whether there is a relationship between vitamin D levels and post-prostatectomy incontinence (PPI).

METHODS: We included patients from our tertiary center who underwent robotic radical prostatectomy (RP) and had their serum vitamin D levels assessed no more than three months before the procedure.Continence status was recorded at one, three, six, and 12 months postoperatively. Urinary continence was defined as either no urine leak or using a pad to feel secure against potential minimal leakage. Patients were divided into groups according to continence status at the 12th postoperative month (group 1: continent patients; group 2: PPI patients). Groups were compared in terms of patient characteristics, previously known PPI risk factors, and serum vitamin D levels.

RESULTS: The entire study cohort consisted of 318 patients. The rate of PPI was 14.5%. Since the mean age, body mass index, and prostate volume were significantly higher in group 2 than in group 1, propensity score matching was applied. Before and after propensity score matching, serum vitamin D levels were higher in group 1 than in group 2 at the 12th postoperative month, but no statistically significant difference was observed; however, after propensity score matching, serum vitamin D levels were significantly higher in continent patients than in incontinent patients at one, three, and six months postoperatively.

CONCLUSIONS: Serum vitamin D may be an essential marker in regaining continence in the early period after RP.

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Published

2025-03-17

How to Cite

Şam, E., Söğütdelen, E., Akka, F., Şeker, K. G., Özlü, D. N., & Güner, E. (2025). Can preoperative vitamin D level be a predictive factor for continence after radical prostatectomy?. Canadian Urological Association Journal, 19(7), E246–50. https://doi.org/10.5489/cuaj.8999

Issue

Vol. 19 No. 7 (2025): CUAJ July

Section

Original Research

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