Proportion of clinically significant prostate cancer diagnosed by systematic template biopsy after negative pre-biopsy multiparametric magnetic resonance imaging and predictive value of prostate-specific antigen density

Authors

  • Mohammad Haroon
  • Paul Sathiadoss
  • Rodney H. Breau
  • Ilias Cagiannos
  • Trevor Flood
  • Luke T. Lavallee
  • Christopher Morash
  • Nicola Schieda The University of Ottawa The Ottawa Hospital Department of Medical Imaging.

DOI:

https://doi.org/10.5489/cuaj.7455

Keywords:

clinically significant prostate cancer, systematic template biopsy, negative pre-biopsy multiparametric MRI, PSA density

Abstract

Biopsy deferral in men with a negative prostate multiparametric magnetic resonance imaging (mpMRI) is gaining popularity in clinical practice, as mpMRI becomes integrated into prostate cancer (PCa) diagnostic pathways.1 However, clinically significant (cs)PCa may be diagnosed at subsequent template biopsy in men with negative pre-biopsy mpMRI.2 This study evaluated the proportion of men with csPCa diagnosis at template biopsy following a negative mpMRI and evaluated prostate-specific antigen (PSA) density as a predictor of future positive template biopsy.

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Published

2021-10-18

How to Cite

Haroon, M., Sathiadoss, P., Breau, R. H., Cagiannos, I., Flood, T., Lavallee, L. T., Morash, C., & Schieda, N. (2021). Proportion of clinically significant prostate cancer diagnosed by systematic template biopsy after negative pre-biopsy multiparametric magnetic resonance imaging and predictive value of prostate-specific antigen density. Canadian Urological Association Journal, 16(3), E178–80. https://doi.org/10.5489/cuaj.7455

Issue

Vol. 16 No. 3 (2022): CUAJ March

Section

Research Letter

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