Effect of SARS-CoV-2 infection on semen parameters


  • Mustafa Bilal Hamarat Health Sciences University, Konya City Hospital, Department of Urology
  • Mehmet Serkan Ozkent Department of Urology, University of Health Sciences, Konya City Hospital, Konya, Turkey.
  • Burak Yılmaz Department of Urology, University of Health Sciences, Konya City Hospital, Konya, Turkey.
  • Salih Yahya Aksanyar Department of Embryology, University of Health Sciences, Konya City Hospital, Konya, Turkey.
  • Kadir Karabacak Department of Urology, Konya Dr. Ali Kemal Belviranlı Obstetrics and Pediatrics Hospital, Konya, Turkey.




SARS-CoV-2, Semen Parameters, Infertility


Introduction: In this study, we aimed to assess the effect of SARSCoV- 2 infection on semen parameters in one group of patients before and after infection.

Methods: Patients were screened if they had a semen analysis performed between October 1, 2019, and December 1, 2020, in the assisted reproduction unit and later had positive polymerase chain reaction (PCR) test for SARS-CoV-2 infection. The patients’ semen parameters were recorded before and after SARS-CoV-2 infection, along with degrees of SARS-CoV-2 infection, dates of SARS-CoV-2 infection, durations between the treatment for SARSCoV- 2 infection and the second semen analysis, time of symptom onset, duration of their symptoms, ages, comorbidities, and any medications patients were taking.

Results: Forty-one patients were included in the study. The mean age of the patients was 31.29±5.95 years. The mean duration from first semen analysis to the PCR test was 7.74±3.03 months. The mean duration between the PCR test and later semen analysis was 2.35±1.35 months. The median sperm concentration for the patients before and after SARS-CoV-2 infection were 24 mil/ml and 13 mil/ml, respectively (p<0.001). The normal morphology percentage before infection was 3.16±0.92, while it was 2.44±1.04 after infection (p=0.011). In 26 patients, the period from the time of infection to the second semen analysis was over 70 days, while this period was less than 70 days in the other 15 patients. In both patient groups, a significant decrease was detected in the sperm concentrations and total sperm count.

Conclusions: In the semen samples we assessed, we observed a significant decrease in the mean sperm concentration, total sperm count, and mean percentage of samples with normal morphology after SARS-CoV-2 infection.


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How to Cite

Hamarat, M. B., Ozkent, M. S., Yılmaz, B. ., Aksanyar, S. Y. ., & Karabacak, K. (2021). Effect of SARS-CoV-2 infection on semen parameters. Canadian Urological Association Journal, 16(3), E173–7. https://doi.org/10.5489/cuaj.7292



Original Research