Uncommon testicular metastasis of a primary neuroendocrine tumour of the lung


  • Ingrid L. Birker Department of Urology, Academic Medical Centre, Amsterdam
  • Johan A. van der Zee Urologist. Sint Lucas Andreas Hospital, Amsterdam
  • Karin M. Keizer Pathologist. Sint Lucas Andreas Hospital, Amsterdam




A 52-year-old male presented with an asymptomatic palpable mass of the right testicle. Ultrasound confirmed the presence of a testicular tumour and a hemicastration was performed. None of the testis cancer-related tumour markers were elevated and histological findings revealed a neuroendocrine carcinoma, possibly a metastasis from another primary site. The radiological findings showed a lesion in the lung, and a positron emission tomography (PET)-scan was made. The PET scan revealed an increased fluorodeoxyglucose (FDG) uptake in the pulmonary lesion. It also showed lymphatic and hepatic metastases. The patient had no complaints besides a palpable testicular mass and was diagnosed with a cT1aN3M1b neuroendocrine carcinoma of the lower left field of the lung, stage IV. To our knowledge, the presentation of testicular metastasis of a neuroendocrine carcinoma of the lung has not been described in the literature. No curative options were available and the patient is being treated with salvage chemotherapy.


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How to Cite

Birker, I. L., van der Zee, J. A., & Keizer, K. M. (2013). Uncommon testicular metastasis of a primary neuroendocrine tumour of the lung. Canadian Urological Association Journal, 7(9-10), e614–7. https://doi.org/10.5489/cuaj.398