Acquired hemophilia A: A rare cause of gross hematuria

Authors

  • Gregory W Hosier Dalhousie University
  • Ross J Mason Dalhousie University
  • K Sue Robinson Dalhousie University
  • Gregory G Bailly Dalhousie University

DOI:

https://doi.org/10.5489/cuaj.3306

Abstract

Acquired hemophilia A is a rare condition caused by spontaneous development of factor VIII inhibitor. This condition most commonly presents with multiple hemorrhagic symptoms and isolated hematuria is exceedingly rare. Early diagnosis is important, as this condition carries a high mortality rate (13‒22%). We present a case of an 82-year-old man with isolated hematuria caused by a factor VIII inhibitor who was successfully treated with recombinant activated factor VII concentrate, as well as prednisone and cyclophosphamide.

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Author Biographies

Gregory W Hosier, Dalhousie University

Medical student

Ross J Mason, Dalhousie University

Urology Resident

K Sue Robinson, Dalhousie University

Division of Hematology, Professor

Gregory G Bailly, Dalhousie University

Department of Urology, Professor

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Published

2015-12-14

How to Cite

Hosier, G. W., Mason, R. J., Robinson, K. S., & Bailly, G. G. (2015). Acquired hemophilia A: A rare cause of gross hematuria. Canadian Urological Association Journal, 9(11-12), E905–7. https://doi.org/10.5489/cuaj.3306