Post-radiation epithelioid angiosarcoma of the urinary bladder and prostate

  • Gang Wang Department of Pathology, University of British Columbia
  • Peter C. Black Department of Urology, Vancouver General Hospital, University of British Columbia
  • Brian F. Skinnider Department of Pathology, Vancouver General Hospital, University of British Columbia
  • Malcolm M. Hayes Department of Pathology, BC Cancer Agency, University of British Columbia
  • Edward C. Jones Department of Pathology, Vancouver General Hospital, University of British Columbia

Abstract

Angiosarcoma of the lower urinary tract is exceedingly rare. A minority of cases are associated with local radiotherapy. Epithelioid angiosarcoma is a variant of angiosarcoma composed of large rounded epithelioid endothelial cells that are positive for cytokeratin on immunostaining. There are only two cases of post-radiation epithelioid angiosarcoma reported in the urinary bladder, and none in the prostate gland. We report a case of epithelioid angiosarcoma involving the urinary bladder and prostate in a patient with a history of radiotherapy for prostatic adenocarcinoma. A brief review of literature regarding post-radiation epithelioid angiosarcomas in the lower urinary tract is discussed.
Published
2016-05-12
How to Cite
Wang, G., Black, P. C., Skinnider, B. F., Hayes, M. M., & Jones, E. C. (2016). Post-radiation epithelioid angiosarcoma of the urinary bladder and prostate. Canadian Urological Association Journal, 10(5-6), E197-200. https://doi.org/10.5489/cuaj.3220
Section
Case Report