Dilemmas in diagnosis and natural history of renal oncocytoma and implications for management

Authors

  • Nikita R. Bhatt Deaprtment of Urology, Adeaide and Meath hospital, Tallaght
  • Niall F. Davis Deaprtment of Urology, Adeaide and Meath hospital, Tallaght
  • Robert Flynn Deaprtment of Urology, Adeaide and Meath hospital, Tallaght
  • Ted McDermott Deaprtment of Urology, Adeaide and Meath hospital, Tallaght
  • J. A. Thornhill Deaprtment of Urology, Adeaide and Meath hospital, Tallaght
  • Rustom P. Manecksha Deaprtment of Urology, Adeaide and Meath hospital, Tallaght

DOI:

https://doi.org/10.5489/cuaj.3144

Keywords:

, oncocytoma, renal/kidney, management, prognosis

Abstract

Introduction: Oncocytomas have traditionally been treated with surgical excision; however, their excellent long-term prognosis has popularized conservative and minimally invasive ablative techniques. We evaluated the evolving management and natural history of renal oncocytomas and investigated the relationship between radiological and histopathological diagnosis.

Methods: We performed a 17-year retrospective cohort study on all patients with a confirmed histopathological diagnosis of renal oncocytoma. The primary outcome variables were long-term outcomes, coexistence with renal cell carcinoma, and development of metastatic disease.

Results: A total of 38 oncocytomas were reported in 36 patients. Of the 36 patients, 29 (81%) were diagnosed incidentally. Oncocytoma was considered in the differential diagnosis in 4 oncocytomas (10.5%). In total, 34 patients underwent early surgical intervention; of these, 27 (79.4%) underwent radical nephrectomy and 7 underwent partial nephrectomy (20.6%). Four patients (11.1%) were managed conservatively with surveillance. No patients developed recurrence or metastatic disease after a median follow-up of 84 months (range: 4–178).

Conclusions: The diagnostic accuracy for imaging modalities in renal oncocytoma is poor. Surveillance or minimally invasive ablative techniques are appropriate in selected patients with biopsyproven oncocytoma that are not increasing in size.

Downloads

Download data is not yet available.

Downloads

Published

2015-10-13

How to Cite

Bhatt, N. R., Davis, N. F., Flynn, R., McDermott, T., Thornhill, J. A., & Manecksha, R. P. (2015). Dilemmas in diagnosis and natural history of renal oncocytoma and implications for management. Canadian Urological Association Journal, 9(9-10), E709–12. https://doi.org/10.5489/cuaj.3144

Issue

Vol. 9 No. 9-10 (2015): CUAJ October

Section

Original Research

License

You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association. This means that you may not, without the prior written permission of the CUA:

  • Post the Article on any Web site
  • Translate or authorize a translation of the Article
  • Copy or otherwise reproduce the Article, in any format, beyond what is permitted under Canadian copyright law, or authorize others to do so
  • Copy or otherwise reproduce portions of the Article, including tables and figures, beyond what is permitted under Canadian copyright law, or authorize others to do so.

The CUA encourages use for non-commercial educational purposes and will not unreasonably deny any such permission request.

You retain your moral rights in and to the Article. This means that the CUA may not assert its copyright in such a way that would negatively reflect on your reputation or your right to be associated with the Article.

The CUA also requires you to warrant the following:

  • That you are the Author(s) and sole owner(s), that the Article is original and unpublished and that you have not previously assigned copyright or granted a licence to any other third party;
  • That all individuals who have made a substantive contribution to the article are acknowledged;
  • That the Article does not infringe any proprietary right of any third party and that you have received the permissions necessary to include the work of others in the Article; and
  • That the Article does not libel or violate the privacy rights of any third party.