Impact of obesity on functional and oncological outcomes in radical perineal prostatectomy

  • Bulent Altay Istanbul Medipol University
  • Bulent Erkurt Istanbul Medipol University
  • Vahit Guzelburc Istanbul Medipol University
  • Murat Can Kiremit Istanbul Medipol University
  • Mustafa Yucel Boz Istanbul Medipol University
  • Selami Albayrak Istanbul Medipol University
Keywords: Prostate cancer, radical perineal prostatectomy, obesity, body mass index

Abstract

Introduction: We evaluated the impact of obesity on perioperative morbidity, functional, and oncological outcomes after radical perineal prostatectomy (RPP).

Methods: A total of 298 consecutive patients underwent RPP at our institution. Patients were categorized into 3 groups based on their body mass index (BMI): Normal weight <25 kg/m2 (Group 1), overweight 25 to <30 kg/m2 (Group 2), and obese ≥30 kg/m2 (Group 3). We compared the groups with respect to perioperative
data, postoperative oncologic, and functional outcomes. Evaluation of urinary continence and erectile function was performed using a patient-reported questionnaire and the International Index of Erectile Function-5 questionnaire, respectively, administered preoperatively and at 3, 6, and 12 months. Limitations included short
follow-up time, retrospective design and lack of a morbidly obese group.

Results: No significant differences were found among the 3 groups with regard to operative time, estimated blood loss, length of hospital stay, catheter removal time, positive surgical margin, and complication rates. At 12 months, 94.7%, 95% and 95% of normal, overweight and obese patients, respectively, were continent (free
of pad use) (p = 0.81). At 12 months, 30.6%, 29.8% and 30.4% of patients had spontaneous erections and were able to penetrate and complete intercourse in Group 1, Group 2, and Group 3, respectively (p = 0.63).

Conclusions: In this cohort of patients, no clinically relevant risks were associated with increasing BMI.

Published
2015-11-04
How to Cite
Altay, B., Erkurt, B., Guzelburc, V., Kiremit, M. C., Boz, M. Y., & Albayrak, S. (2015). Impact of obesity on functional and oncological outcomes in radical perineal prostatectomy. Canadian Urological Association Journal, 9(11-12), E766-9. https://doi.org/10.5489/cuaj.3094
Section
Original Research