Chemotherapy for prostate cancer: Clinical practice in Canada

Authors

  • Fred Saad Chairman, National Cancer Institute of Canada Clinical Trials Genitourinary Group (NCIC-CTG G-U) and Canadian Urologic Oncology Group (CUOG); Professor and Chief of Urology, Director of Urologic Oncology, Endowed Chair in Prostate Cancer, Centre Hospitalier de l’Université de Montréal, Montreal, QC
  • Jamil Asselah Medical Oncologist, McGill University Health Centre, Montreal, QC

DOI:

https://doi.org/10.5489/cuaj.273

Abstract

Whereas prostate cancer was once deemed unresponsive to chemotherapy, there is now evidence that patients with metastatic castration-resistant prostate cancer can obtain a survival benefit from both first-line (docetaxel-based) and second-line (cabazitaxelbased) chemotherapy. The side effects of these agents have been shown to be predictable and manageable, particularly in North American centres. However, patient selection remains a key issue, with the aim of delivering each line of treatment at a time when the individual patient remains fit and well enough to tolerate acytotoxic regimen. Hence, it is increasingly important for urologists and oncologists to work together to ensure timely consideration ofthe chemotherapeutic approach before it is precluded by a decline in performance status.

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Published

2013-02-19

How to Cite

Saad, F., & Asselah, J. (2013). Chemotherapy for prostate cancer: Clinical practice in Canada. Canadian Urological Association Journal, 7(1-2-S1), S5-S10. https://doi.org/10.5489/cuaj.273

Issue

Vol. 7 No. 1-2-S1 (2013): CUAJ February 2013-Suppl 1

Section

Review

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