Update on medical expulsive therapy for distal ureteral stones: Beyond alpha-blockers

Authors

  • Derek Bos McMaster University
  • Anil Kapoor McMaster University

DOI:

https://doi.org/10.5489/cuaj.2472

Keywords:

urolithiasis, medical expulsive therapy, alpha-blockers, ureteric stones

Abstract

Medical expulsive therapy (MET) has been described as an effective conservative treatment option in the initial management of small distal ureteral stones. Therapies that have been investigated include alpha-blockers, calcium channel blockers, corticosteroids, and most recently phosphodiesterase-5 inhibitors (PDE5) inhibitors. While alpha-blockers are currently the only recommended monotherapy, corticosteroids have received increased attention as a potential useful adjunct in the medical management of distal stones. PDE5 inhibitors are a novel treatment alternative, requiring further investigation. This review provides an overview of recent MET best practices, with a focus on novel therapies beyond alpha blockers.

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Author Biographies

Derek Bos, McMaster University

McMaster Urology Resident

Anil Kapoor, McMaster University

Professor of Surgery (Urology), McMaster University

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Published

2014-12-15

How to Cite

Bos, D., & Kapoor, A. (2014). Update on medical expulsive therapy for distal ureteral stones: Beyond alpha-blockers. Canadian Urological Association Journal, 8(11-12), 442–5. https://doi.org/10.5489/cuaj.2472

Issue

Vol. 8 No. 11-12 (2014): CUAJ December

Section

Review

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