Paraneoplastic production of heparin-like anticoagulant in a patient with metastatic transitional cell carcinoma

Authors

  • Kelly N. Fahl Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY
  • Stephen A. Poon Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY
  • Ketan K. Badani Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY
  • Mitchell C. Benson Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY

DOI:

https://doi.org/10.5489/cuaj.1165

Abstract

It has been reported that patients with bladder cancer have widely
varying paraneoplastic consequences, including metabolic, dermatologic,
myopathic and neurologic disturbances. We report a case of a
52-year-old man with advanced transitional cell carcinoma and liver
metastases, who developed a severe coagulopathy following robotic
radical cystoprostatectomy due to circulating heparin-like substances
prior to onset of liver failure. Heparin-like anticoagulant production is
a rare paraneoplastic effect documented in concert with transitional
cell carcinoma, breast carcinoma and hematological malignancies.

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Author Biographies

Kelly N. Fahl, Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY

Stephen A. Poon, Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY

Ketan K. Badani, Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY

Mitchell C. Benson, Department of Urology, Columbia University College of Physicians & Surgeons, New York, NY

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How to Cite

Fahl, K. N., Poon, S. A., Badani, K. K., & Benson, M. C. (2013). Paraneoplastic production of heparin-like anticoagulant in a patient with metastatic transitional cell carcinoma. Canadian Urological Association Journal, 3(5), E61-E63. https://doi.org/10.5489/cuaj.1165

Issue

Vol. 3 No. 5 (2009): CUAJ October

Section

Case Report

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