Composite paraganglioma-ganglioneuroma of the urinary bladder: a rare neoplasm causing hemodynamic crisis at tumour resection

Authors

  • C-H. Chen Department of Pathology and Molecular Medicine, Kingston General Hospital and Queen’s University, Kingston, ON
  • Alexander H. Boag Department of Pathology and Molecular Medicine, Kingston General Hospital and Queen’s University, Kingston, ON
  • Darren T. Beiko Department of Urology, Kingston General Hospital and Queen’s University, Kingston, ON
  • Robert Siemens Department of Urology, Kingston General Hospital and Queen’s University, Kingston, ON
  • Alison Froese Department of Anesthesiology, Kingston General Hospital and Queen’s University, Kingston, ON
  • Phillip A. Isotalo Department of Pathology and Molecular Medicine, Kingston General Hospital and Queen’s University, Kingston, ON

DOI:

https://doi.org/10.5489/cuaj.1160

Abstract

A 64-year-old man presented with gross painless hematuria.
Cystoscopy revealed a submucosal bladder neck mass covered
by normal urothelium. During transurethral resection, the patient
developed hemodynamic crisis including sinus bradycardia.
Histopathologic examination revealed a primary bladder composite
paraganglioma-ganglioneuroma (CPG). The patient underwent
partial cystectomy and is symptom-free after one year. Bladder
CPGs are extremely rare neoplasms that may result in lifethreatening
catecholamine secretion, especially during tumour
manipulation. These tumours require complete surgical excision
and should be included in the differential diagnosis of any solitary
bladder mass covered by normal urothelium, especially when
there is a history of hypertension or micturition attacks.

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Author Biographies

C-H. Chen, Department of Pathology and Molecular Medicine, Kingston General Hospital and Queen’s University, Kingston, ON

Alexander H. Boag, Department of Pathology and Molecular Medicine, Kingston General Hospital and Queen’s University, Kingston, ON

Darren T. Beiko, Department of Urology, Kingston General Hospital and Queen’s University, Kingston, ON

Robert Siemens, Department of Urology, Kingston General Hospital and Queen’s University, Kingston, ON

Alison Froese, Department of Anesthesiology, Kingston General Hospital and Queen’s University, Kingston, ON

Phillip A. Isotalo, Department of Pathology and Molecular Medicine, Kingston General Hospital and Queen’s University, Kingston, ON

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How to Cite

Chen, C.-H., Boag, A. H., Beiko, D. T., Siemens, R., Froese, A., & Isotalo, P. A. (2013). Composite paraganglioma-ganglioneuroma of the urinary bladder: a rare neoplasm causing hemodynamic crisis at tumour resection. Canadian Urological Association Journal, 3(5), E45-E48. https://doi.org/10.5489/cuaj.1160

Issue

Vol. 3 No. 5 (2009): CUAJ October

Section

Case Report

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