Case: Spontaneous regression of post-radical prostatectomy prostate-specific antigen elevation without adjuvant therapy in a patient with lymph node metastasis

Taehyoung Lee, Yanbo Guo, Saahil Vij, Rahul Bansal, Nathan C. Wong, Bobby Shayegan

Abstract


Prostate cancer remains the most frequently diagnosed cancer among men. The combination of clinical stage, serum prostatespecific antigen (PSA), and Gleason score (biopsy) assists in predictive assessment of pathological stage and prognosis. Furthermore, pathological criteria, including Gleason score, surgical margin status, extracapsular extension, seminal vesicle invasion, and lymph node involvement, provide prognostication in patients undergoing radical prostatectomy (RP). In this paper, we present a case of a patient with high-risk prostate cancer with persistent PSA elevation post-RP who experiences a complete regression of PSA without any adjuvant therapy. To the authors’ knowledge, such a finding has not been described in the literature previously.

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DOI: http://dx.doi.org/10.5489/cuaj.4324

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