Can radiotherapy be a viable salvage treatment option for the relapsed seminoma confined to the infra-diaphragm region recurring after primary chemotherapy for bulky stage II seminoma?

Authors

  • Richard Choo Department of Radiation Oncology, Mayo Clinic, Rochester, MN
  • Fernando Quevedo Department of Medical Oncology, Mayo Clinic, Rochester, MN
  • Christopher S. Choo Department of Radiation Oncology, Mayo Clinic, Rochester, MN
  • Michael Blute Department of Urology, Mayo Clinic, Rochester, MN

DOI:

https://doi.org/10.5489/cuaj.937

Abstract

There has been a paucity of research describing a potential role
of radiotherapy as salvage treatment for recurrent seminoma following
primary chemotherapy for bulky stage IIC seminoma. We
report a case of a bulky stage IIC seminoma relapsed in the pelvis
after primary chemotherapy and surgery for post-chemotherapy
residual mass, which was subsequently salvaged with radiotherapy.
The patient has remained free of relapse at 3.7 years post-salvage
radiotherapy. This case demonstrates that radiotherapy can be a
salvage therapeutic option for recurrent seminoma following primary
chemotherapy for bulky stage IIC seminoma, provided that
the recurrent tumour is confined to a limited area of the infradiaphragmatic
region. There is a need for further study to examine
the potential role of radiotherapy as a salvage therapeutic tool for
post-chemotherapy recurrent seminoma.

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Author Biographies

Richard Choo, Department of Radiation Oncology, Mayo Clinic, Rochester, MN

Fernando Quevedo, Department of Medical Oncology, Mayo Clinic, Rochester, MN

Christopher S. Choo, Department of Radiation Oncology, Mayo Clinic, Rochester, MN

Michael Blute, Department of Urology, Mayo Clinic, Rochester, MN

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How to Cite

Choo, R., Quevedo, F., Choo, C. S., & Blute, M. (2013). Can radiotherapy be a viable salvage treatment option for the relapsed seminoma confined to the infra-diaphragm region recurring after primary chemotherapy for bulky stage II seminoma?. Canadian Urological Association Journal, 4(5), E137-E140. https://doi.org/10.5489/cuaj.937

Issue

Vol. 4 No. 5 (2010): CUAJ October

Section

Case Report

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