Screening guidelines for people at increased risk for prostate cancer

Authors

  • Justin Lorentz University of Toronto
  • Julia Woollcombe University of Toronto
  • Andrew Loblaw University of Toronto
  • Stanley Liu University of Toronto
  • Danny Vesprini University of Toronto

DOI:

https://doi.org/10.5489/cuaj.8710

Keywords:

prostate cancer genetics, family history, ancestry, increased risk for prostate cancer, hereditary prostate cancer, cancer screening

Abstract

Individuals at increased risk for prostate cancer (PCa) are inconsistently defined in national and international guidelines. The National Comprehensive Cancer Network (NCCN) defines people at increased risk for PCa to include those with a concerning family history, West African/Caribbean/African-American individuals, and those who have germline mutations in known PCa-related genes. Recommendations for screening are also inconsistently defined in national and international guidelines. The NCCN and American Urological Association recommend that individuals at increased risk for PCa be screened with prostate-specific antigen and digital rectal exam starting at age 40. Defining increased risk groups and defining lifetime risk is an ongoing academic process that can be facilitated through patient registries of these cohorts at academic centers.

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Published

2024-06-10

How to Cite

Lorentz, J., Woollcombe , J. ., Loblaw , A. ., Liu, S. ., & Vesprini , D. (2024). Screening guidelines for people at increased risk for prostate cancer. Canadian Urological Association Journal, 18(10), E301–7. https://doi.org/10.5489/cuaj.8710

Issue

Vol. 18 No. 10 (2024): CUAJ October

Section

Review

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