Cases – Clear-cell urothelial carcinoma of the bladder


  • Carolyn MacLeod Division of Urology, Department of Surgery, Western University. London, Ontario, Canada
  • Ernest P. Chan Western University
  • Kamilia Rizkalla Department of Pathology and Laboratory Medicine, Western University. London, Ontario, Canada.
  • Alp Sener
  • Jeffrey Campbell Department of Surgery, Division of Urology, Western University, London, ON, Canada



clear cell; variant histology; urothelial carcinoma; bladder cancer; cystectomy


Variant histology in urothelial carcinoma of the bladder is often associated with advanced stage at presentation and poor prognosis. Clear-cell is a rare histological variant of urothelial carcinoma of the bladder, with only 22 cases reported in current literature. Most cases reported have resulted in poor prognoses despite aggressive management. The two cases described in this report add to the sparse literature regarding clear-cell urothelial carcinoma (CCUC) of the bladder and expand on possible management options for treatment.


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How to Cite

MacLeod, C., Chan, E. P., Rizkalla, K., Sener, A., & Campbell, J. (2021). Cases – Clear-cell urothelial carcinoma of the bladder. Canadian Urological Association Journal, 15(12), E672–5.



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