Systematic review of therapy for men with overactive bladder

Authors

  • Christopher Chapple Consultant Urological Surgeon, Sheffield Teaching Hospitals NHS Foundation Trust, Department of Urology, The Royal Hallamshire Hospital, Sheffield, UK

DOI:

https://doi.org/10.5489/cuaj.714

Abstract

Lower urinary tract symptoms (LUTS) can have multiple causes in
men. Overactive bladder (OAB) is an empirical diagnosis used as
the basis for initial management after assessing symptoms, physical
findings, urinalysis and other indicated evaluations. In men,
the diagnosis is complicated by the potential of benign prostatic
hyperplasia (BPH), which is a histological diagnosis. Although
storage symptoms (i.e., those associated with OAB) are the most
bothersome group of LUTS in men with BPH, these patients are
usually treated with BPH rather than OAB drugs. The standard
pharmacologic treatment of patients with bothersome voiding and
storage LUTS at low risk of progression should be an α1-AR antagonist.
The combination α1-AR antagonist + antimuscarinic agent
is an appropriate and valid option for male patients with voiding
symptoms and persistent storage symptoms.

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Author Biography

Christopher Chapple, Consultant Urological Surgeon, Sheffield Teaching Hospitals NHS Foundation Trust, Department of Urology, The Royal Hallamshire Hospital, Sheffield, UK

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How to Cite

Chapple, C. (2013). Systematic review of therapy for men with overactive bladder. Canadian Urological Association Journal, 5(5-S2), S143-S145. https://doi.org/10.5489/cuaj.714