Carcinosarcoma of the bladder: case report and review of the literature

Authors

  • Arda Akoluk Yeditepe University School of Medicine, Istanbul,Turkey
  • Yagil Barazani Sol and Margaret Berger Department of Urology, Beth Israel Medical Center, New York, NY
  • Denisa Slova Department of Pathology, Beth Israel Medical Center, New York, NY
  • Sovrin Shah Sol and Margaret Berger Department of Urology, Beth Israel Medical Center, New York, NY
  • Basir Tareen Sol and Margaret Berger Department of Urology, Beth Israel Medical Center, New York, NY

DOI:

https://doi.org/10.5489/cuaj.678

Abstract

Primary osteosarcomas of the bladder account for about 0.04% of
bladder neoplasms. Most of the patients in the literature expired
within 6 months and, in almost all of the cases in the literature,
radical cystectomy with postoperative chemotherapy was the
treatment choice. A 79-year-old gentleman presented with gross
hematuria. Cystoscopy demonstrated a 2- to 3-cm tumour along the
lateral wall of the bladder. The tumour was resected incompletely
via initial transurethral resection of bladder tumour (TURBT), and
a second TURBT was subsequently performed to fully resect the
residual mass. Surgical pathology from these 2 resections revealed
osteosarcoma with invasion into the muscularis propria. A
cystoprostatectomy was performed and final pathologic specimen
revealed high-grade CIS without evidence of residual osteosarcoma.
Postoperatively, the patient did not receive chemotherapy or
radiation and currently remains disease-free 2 years post-radical
cystectomy. Only 33 well-documented cases of primary osteosarcoma
of the bladder have been reported to date. However, there
are only 3 cases in which TURBT resulted in complete resection.

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Author Biographies

Arda Akoluk, Yeditepe University School of Medicine, Istanbul,Turkey

Yagil Barazani, Sol and Margaret Berger Department of Urology, Beth Israel Medical Center, New York, NY

Denisa Slova, Department of Pathology, Beth Israel Medical Center, New York, NY

Sovrin Shah, Sol and Margaret Berger Department of Urology, Beth Israel Medical Center, New York, NY

Basir Tareen, Sol and Margaret Berger Department of Urology, Beth Israel Medical Center, New York, NY

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How to Cite

Akoluk, A., Barazani, Y., Slova, D., Shah, S., & Tareen, B. (2013). Carcinosarcoma of the bladder: case report and review of the literature. Canadian Urological Association Journal, 5(4), E69-E73. https://doi.org/10.5489/cuaj.678

Issue

Section

Case Report