Diabetes and elevated urea level predict for uretero-ileal stricture after radical cystectomy and ileal conduit formation

Authors

  • Nathan Hoag Department of Urology, Austin Hospital, University of Melbourne http://orcid.org/0000-0002-6840-7152
  • Nathan Papa Department of Urology, Austin Hospital, University of Melbourne
  • Bhawanie Koonj Beharry Department of Urology, Austin Hospital, University of Melbourne
  • Nathan Lawrentschuk Department of Urology, Austin Hospital, University of Melbourne
  • Danny Chiu Department of Urology, Austin Hospital, University of Melbourne
  • Shomik Sengupta Department of Urology, Austin Hospital, University of Melbourne
  • Damien Bolton Department of Urology, Austin Hospital, University of Melbourne

DOI:

https://doi.org/10.5489/cuaj.3848

Abstract

Introduction: Benign uretero-ileal anastomotic stricture is a significant complication following radical cystectomy and ileal conduit urinary diversion after radical cystectomy. We examined risk factors for stricture formation to predict those at greatest stricture risk.

Methods: A retrospective chart review was conducted for patients undergoing radical cystectomy and ileal conduit diversion between 2002 and 2012. Demographic data and patient variables were analyzed to determine risk factors for uretero-ileal stricture using multivariate logistic regression.

Results: Over the study period, 133 patients underwent cystectomy and ileal conduit formation, with 14 (10.5%) developing ureteroileal anastomotic stricture. Diabetes and elevated serum urea level (defined as >7.1 mmol/L) were associated with increased risk for development of uretero-ileal stricture (odds ratio 4.31 and 4.28, respectively; p<0.05 for each).

Conclusions: In this patient cohort, diabetes and elevated serum urea level were predictive for the development of uretero-ileal anastomotic stricture. Further prospective study with larger patient samples is required.

Downloads

Download data is not yet available.

Downloads

Published

2017-03-16

How to Cite

Hoag, N., Papa, N., Koonj Beharry, B., Lawrentschuk, N., Chiu, D., Sengupta, S., & Bolton, D. (2017). Diabetes and elevated urea level predict for uretero-ileal stricture after radical cystectomy and ileal conduit formation. Canadian Urological Association Journal, 11(3-4), E88–92. https://doi.org/10.5489/cuaj.3848

Issue

Vol. 11 No. 3-4 (2017): CUAJ March

Section

Original Research

License

You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association. This means that you may not, without the prior written permission of the CUA:

  • Post the Article on any Web site
  • Translate or authorize a translation of the Article
  • Copy or otherwise reproduce the Article, in any format, beyond what is permitted under Canadian copyright law, or authorize others to do so
  • Copy or otherwise reproduce portions of the Article, including tables and figures, beyond what is permitted under Canadian copyright law, or authorize others to do so.

The CUA encourages use for non-commercial educational purposes and will not unreasonably deny any such permission request.

You retain your moral rights in and to the Article. This means that the CUA may not assert its copyright in such a way that would negatively reflect on your reputation or your right to be associated with the Article.

The CUA also requires you to warrant the following:

  • That you are the Author(s) and sole owner(s), that the Article is original and unpublished and that you have not previously assigned copyright or granted a licence to any other third party;
  • That all individuals who have made a substantive contribution to the article are acknowledged;
  • That the Article does not infringe any proprietary right of any third party and that you have received the permissions necessary to include the work of others in the Article; and
  • That the Article does not libel or violate the privacy rights of any third party.