Androgen secreting giant adrenocortical carcinoma with no metastases: A case report and review of the literature

Authors

  • Fatih Uruc Fatih Sultan Mehmet Research and Training Hospital
  • Ahmet Urkmez Fatih Sultan Mehmet Research and Training Hospital
  • Ozgur Haki Yuksel Fatih Sultan Mehmet Research and Training Hospital
  • Aytac Sahin Fatih Sultan Mehmet Research and Training Hospital
  • Ayhan Verit Fatih Sultan Mehmet Research and Training Hospital

DOI:

https://doi.org/10.5489/cuaj.2867

Keywords:

Giant, adrenocortical carcinoma, androgen secreting, non-metastasing, mitotane

Abstract

Functional adrenocortical carcinoma (ACC) is a very rare disease with a poor prognosis. Over half (60%) of ACCs bigger than 6 cm synthesize hormones; hormone-secreting ACCs generally include virilization, feminization or Cushing syndrome. Besides, 82% of ACCs are metastatic at the time of diagnosis. While a 48-year-old female patient was examined for abdominal pain and flushing, we detected a non-metastasizing mass (23 × 18 × 16 cm) in the adrenal lodge. The mass was extracted en bloc during open exploration and its histopathology was reported as ACC. We review the literature and report the largest androgen-producing, clinically silent ACC mass cited in the literature so far.

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Published

2015-09-09

How to Cite

Uruc, F., Urkmez, A., Yuksel, O. H., Sahin, A., & Verit, A. (2015). Androgen secreting giant adrenocortical carcinoma with no metastases: A case report and review of the literature. Canadian Urological Association Journal, 9(9-10), E644–7. https://doi.org/10.5489/cuaj.2867

Issue

Vol. 9 No. 9-10 (2015): CUAJ September

Section

Case Report

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