Primary perivascular epithelioid cell tumour (PEComa) of the prostate

Authors

  • Alper Eken Acıbadem University
  • Yesim Saglican Acibadem Maslak Hospital

DOI:

https://doi.org/10.5489/cuaj.1752

Keywords:

prostate, perivascular epithelioid cell tumor, PEComa, HMB-45, mesenchymal.

Abstract

Perivascular epithelioid cell tumours (PEComas) are a family of rare mesenchymal tumours arising in various anatomic locations. PEComas are defined by the presence of perivascular epithelioid cells that coexpress muscle and melanotic markers, especially HMB-45. They have unpredictable biological behaviour and are mostly benign, but some tumours can become unresectable or metastatic. Surgical resection, when possible, is the best treatment option. Radiation therapy, cytotoxic chemotherapy or immunotherapy have been reported as treatment options, either alone or in combination therapy. Prostatic PEComa is extremely rare, with only 1 malignant case reported. We report the first case of prostatic PEComa, which was benign and treated with transurethral resection.

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Author Biographies

Alper Eken, Acıbadem University

Urology

Yesim Saglican, Acibadem Maslak Hospital

Pathology

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Published

2014-06-19

How to Cite

Eken, A., & Saglican, Y. (2014). Primary perivascular epithelioid cell tumour (PEComa) of the prostate. Canadian Urological Association Journal, 8(5-6), e455–7. https://doi.org/10.5489/cuaj.1752

Issue

Section

Case Report

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