An ALK translocation positive carcinoma of the lung presenting as uremia due to bilateral

Authors

  • Shilo Rosenberg Hebrew University, Hadassah Medical Organization
  • Ran Katz
  • Dov Pode
  • N. Ofer Gofr

DOI:

https://doi.org/10.5489/cuaj.172

Keywords:

lung adenocarcinoma malignant retroperitoneal fibrosis crizotinib

Abstract

We describe an unusual presentation of metastatic lung adenocarcinoma as malignant retroperitoneal fibrosis (MRPF). The diagnostic challenge, due to the small solitary lung mass and absence of a discrete retroperitoneal mass, was overcome by diagnostic laparoscopy. Molecular analysis of tissue acquired was positive for ALK gene rearrangement. Treatment of the patient with crizotinib reversed MRPF. He was weaned off the nephrostomy tubes and is with stable renal function 11 months after diagnosis.

Downloads

Download data is not yet available.

Author Biography

Shilo Rosenberg, Hebrew University, Hadassah Medical Organization

Urology, senior urologist

Downloads

Published

2013-07-02

How to Cite

Rosenberg, S., Katz, R., Pode, D., & Gofr, N. O. (2013). An ALK translocation positive carcinoma of the lung presenting as uremia due to bilateral. Canadian Urological Association Journal, 7(7-8), E490–4. https://doi.org/10.5489/cuaj.172

Issue

Vol. 7 No. 7-8 (2013): CUAJ July

Section

Case Report

License

You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association. This means that you may not, without the prior written permission of the CUA:

  • Post the Article on any Web site
  • Translate or authorize a translation of the Article
  • Copy or otherwise reproduce the Article, in any format, beyond what is permitted under Canadian copyright law, or authorize others to do so
  • Copy or otherwise reproduce portions of the Article, including tables and figures, beyond what is permitted under Canadian copyright law, or authorize others to do so.

The CUA encourages use for non-commercial educational purposes and will not unreasonably deny any such permission request.

You retain your moral rights in and to the Article. This means that the CUA may not assert its copyright in such a way that would negatively reflect on your reputation or your right to be associated with the Article.

The CUA also requires you to warrant the following:

  • That you are the Author(s) and sole owner(s), that the Article is original and unpublished and that you have not previously assigned copyright or granted a licence to any other third party;
  • That all individuals who have made a substantive contribution to the article are acknowledged;
  • That the Article does not infringe any proprietary right of any third party and that you have received the permissions necessary to include the work of others in the Article; and
  • That the Article does not libel or violate the privacy rights of any third party.