Recurrent transitional cell carcinoma of the bladder: A mixed nested variant case report and literature review

Authors

  • Ettore De Berardinis Sapienza Rome University, Policlinico Umberto I, Rome, Italy
  • Gian Maria Busetto Sapienza Rome University, Policlinico Umberto I, Rome, Italy
  • Riccardo Giovannone Sapienza Rome University, Policlinico Umberto I, Rome, Italy
  • Gabriele Antonini Sapienza Rome University, Policlinico Umberto I, Rome, Italy
  • Mariarosaria Di Placido, Sapienza Rome University, Policlinico Umberto I, Rome, Italy
  • Vincenzo Gentile Sapienza Rome University, Policlinico Umberto I, Rome, Italy

DOI:

https://doi.org/10.5489/cuaj.160

Abstract

Nested variant of urothelial cell carcinoma (NVUC) is a rare histological

entity, with about 80 reported cases. It has a deceptively

benign appearance with an aspect characterized by confluent

small nest or urothelial’s cell tubules. This tumour often resembles

inverted papilloma, von Brunn’s nests (VBNs), cystitis cystica,

nephrogenic metaplasia and sometimes usual transitional cell cancer.

It is very important to be able to distinguish between benign

lesions and nested variant bladder cancer because, in spite of its

bland morphology, there is evidence that it behaves aggressively.

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Author Biographies

Ettore De Berardinis, Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Gian Maria Busetto, Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Riccardo Giovannone, Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Gabriele Antonini, Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Mariarosaria Di Placido,, Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Vincenzo Gentile, Sapienza Rome University, Policlinico Umberto I, Rome, Italy

Sapienza Rome University, Policlinico Umberto I, Rome, Italy

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Published

2012-12-17

How to Cite

De Berardinis, E., Busetto, G. M., Giovannone, R., Antonini, G., Di Placido, M., & Gentile, V. (2012). Recurrent transitional cell carcinoma of the bladder: A mixed nested variant case report and literature review. Canadian Urological Association Journal, 6(2). https://doi.org/10.5489/cuaj.160

Issue

Vol. 6 No. 2 (2012): CUAJ April

Section

Case Report

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