Alpha-fetoprotein and carbohydrate antigen 19-9 producing advanced adenocarcinoma of renal pelvis and ureter

Authors

  • Kai Yang Department of Urology, School of Medicine, Zhejiang University, Zhejiang Province, China
  • Xiang-Yi Zheng Department of Urology, School of Medicine, Zhejiang University, Zhejiang Province, China
  • Yan-Li Wang Department of Pathology, School of Medicine, Zhejiang University, Zhejiang Province, China
  • Kui Zhao PET Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, China

DOI:

https://doi.org/10.5489/cuaj.1544

Abstract

Tumour markers producing primary adenocarcinoma of upper urinary tract is extremely rare. We report a case of advanced adenocarcinoma of renal pelvis and ureter with highly elevated serum levels of alpha-fetoprotein (AFP) and carbohydrate antigen 19-9 (CA19-9). This 66-year-old man was diagnosed with left renal pelvic and ureteral tumours with para-aortic lymph node swelling, with no evidence of abnormality in his digestive or reproductive system. He was successfully treated with left nephroureterectomy and lymph node dissection followed by gemcitabine/carboplatin chemotherapy and the serum levels of AFP and CA19-9 decreased to normal. Pathological examination revealed a moderately or poorly differentiated intestinal-type adenocarcinoma with para-aortic lymph node metastasis. The patient was followed up for 11 months after surgery without recurrence.

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Published

2013-11-08

How to Cite

Yang, K., Zheng, X.-Y., Wang, Y.-L., & Zhao, K. (2013). Alpha-fetoprotein and carbohydrate antigen 19-9 producing advanced adenocarcinoma of renal pelvis and ureter. Canadian Urological Association Journal, 7(11-12), e750–3. https://doi.org/10.5489/cuaj.1544

Issue

Vol. 7 No. 11-12 (2013): CUAJ November

Section

Case Report

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