Hematospermia and xanthogranulomatous prostatitis: An unusual onset of a rare diagnosis

Authors

  • Antonio Luigi Pastore Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy
  • Giovanni Palleschi Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy
  • Andrea Fuschi Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy
  • Natale Porta Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Histopathology Unit - I.C.O.T, Latina, Italy
  • Bruna Cerbelli Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Histopathology Unit - I.C.O.T, Latina, Italy
  • Claudio Di Cristofano Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Histopathology Unit - I.C.O.T, Latina, Italy
  • Vincenzo Petrozza Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Histopathology Unit - I.C.O.T, Latina, Italy
  • Antonio Carbone Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy

DOI:

https://doi.org/10.5489/cuaj.1525

Keywords:

Xanthogranulomatous prostatitis, hematospermia, lower urinary tract symptoms, xanthomatous cells

Abstract

Xanthogranulomatous prostatitis is a rare type of granulomatous prostatitis, with very few cases described. We report the clinical, radiological and pathological findings of 5 cases of xanthogranulomatous prostatitis. All patients came for recurrent episodes of hematospermia (associated with fever in 3 patients). All patients suffered from lower urinary tract symptoms and an increased prostate-specific antigen (PSA) level associated with a suspicious digital rectal examination (DRE); however, at biopsy, the results were negative for xanthogranulomatous prostatitis. Due to persistent severe bladder outlet obstruction, after unsuccessful medical treatments, all patients underwent transurethral resection of prostate (TURP). Final histological examination revealed a xanthogranulomatous prostatitis. The xanthogranulomatous prostatitis can be an incidental finding after TURP and it can simulate prostatic malignancy with PSA elevation.

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Published

2013-12-05

How to Cite

Pastore, A. L., Palleschi, G., Fuschi, A., Porta, N., Cerbelli, B., Di Cristofano, C., Petrozza, V., & Carbone, A. (2013). Hematospermia and xanthogranulomatous prostatitis: An unusual onset of a rare diagnosis. Canadian Urological Association Journal, 7(11-12), e820–2. https://doi.org/10.5489/cuaj.1525

Issue

Vol. 7 No. 11-12 (2013): CUAJ December

Section

Case Series

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