Inverted papilloma of the ureter: study of a rare case with emphasis on clinicopathologic implications

Authors

  • Nikolaos Mertziotis Department of Urology, Mitera Clinic, Hygeia group, Marousi, Attica
  • Diomidis Kozyrakis Department of Urology, Mitera Clinic, Hygeia group, Marousi, Attica
  • Andreas Petrolekas Department of Urology, Henry Denaunt Hospital, Marousi, Attica
  • Maria Terzi Department of Pathology, Mitera Clinic, Hygeia group Marousi, Attica
  • Nikiforos Kapranos Department of Molecular Pathology, Mitera Clinic, Hygeia group Marousi, Attica

DOI:

https://doi.org/10.5489/cuaj.134

Abstract

A 62-year old male patient presented complaining of intermittent macroscopic hematuria. The ultrasonographic investigation revealed a hydronephrosis of remarkable degree with indiscreterenal parenchyma. The abdominal computed tomography scan identified a ureteral lesion with proximal dilatation, hydronephrosis and a functionless ipsilateral renal unit. The retrograde urography showed a 4-cm lesion with multiple filling defects and a smooth contour. The endoscopic examination showed an exophytic lesion, highly suspicious for malignancy. Urine cytology revealed atypia. Right nephroureterectomy was performed and the pathology revealed a ureteral inverted papilloma (UIP). Polymerase chain reaction examination for the presence of human papilloma virus, using GP5+/6+ consensus primers, was negative. The presence UIP should be considered in patients with urotheleal lesions in the ureter when the diagnostic workup for malignancy is inconclusive. The clinical course of the disease seems to be favorable.

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Published

2012-12-13

How to Cite

Mertziotis, N., Kozyrakis, D., Petrolekas, A., Terzi, M., & Kapranos, N. (2012). Inverted papilloma of the ureter: study of a rare case with emphasis on clinicopathologic implications. Canadian Urological Association Journal, 6(6), e274–6. https://doi.org/10.5489/cuaj.134

Issue

Section

Case Report