The effect of alpha blockers on uroflowmetric parameters in different voiding positions
Introduction: We assessed the effect of different voiding positionson uroflowmetric parameters and post-void residual (PVR)urine volume in symptomatic benign prostatic hyperplasia (BPH)patients. We also evaluated the effect of alpha blockers on PVR indifferent voiding positions.
Methods: The study was performed with 110 BPH patients over 50years old. In total, 4 uroflowmetries were performed in all patients:2 patients in the sitting position and 2 in the standing position. PVRwas measured with transabdominal ultrasonography. Also, patientswere divided into two groups according to the alpha adrenergicblocker treatment; the effect of this treatment on their uroflowmetricparameters in different positions was evaluated.
Results: Maximum flow rate (Qmax) and average flow rate (Qave)were significantly higher in patients in the sitting position, butthere were no differences in other uroflowmetric parameters andPVR volume (Qmax: 15.5±5.9 mL/s vs. 13.7±5.2 mL/s, Qave:11.4±4.6 mL/s vs. 10.7± 3.9 mL/s, respectively; p < 0.05). TheQmax and Qave were significantly higher in sitting position, comparedto the standing position, in both alpha adrenergic treatmentand non-treated groups; again, there were no differences in otheruroflowmetric parameters and PVR volume.
Conclusion: Qmax and Qave values were significantly higher inthe sitting position. Alpha blockers did not affect any change.
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