Diagnosis and prognosis of malignant mesothelioma of the tunica vaginalis testis

Authors

  • Bo Hai Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China
  • Yu Yang Center for Molecular Physiology Research, Children’s National Medical Center, Washington DC
  • Yajun Xiao Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China
  • Bing Li Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China
  • Chaohui Chen Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China

DOI:

https://doi.org/10.5489/cuaj.123

Abstract

Objectives: The objective of this study is to evaluate the diagnosis and prognosis of malignant mesothelioma of the tunica vaginalis testis through an additional 6 patients with urogenital mesothelioma.

Methods: Six patients with urogenital mesothelioma who underwent adequate surgical procedures and histopathologic analysis from 1990 to 2009 were identified and retrospectively reviewed.

Results: Six patients between the ages of 26 and 78 years with urogenital mesothelioma, 5 of which originated in the scrotum and 1 in the spermatic cord. Histopathologic analysis showed that CK5/6 and calretinin were positive in all cases, 5 cases were positive for vimentin, and 1 case showed focal weak positive reaction with MOC3, but none of the cases stained for CEA or CD15. The overall recurrence rate of urogenital mesothelioma after surgery was 5/6, including local recurrences and fatalities due to tumour.

Conclusions: In cases of mesothelioma of the tunica vaginalis testis, the histopathologic markers we chose helped confirm the histopathological diagnosis; adequate surgical procedures are typically not curative, and this tumour is often fatal.

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Published

2012-12-13

How to Cite

Hai, B., Yang, Y., Xiao, Y., Li, B., & Chen, C. (2012). Diagnosis and prognosis of malignant mesothelioma of the tunica vaginalis testis. Canadian Urological Association Journal, 6(6), e238–41. https://doi.org/10.5489/cuaj.123

Issue

Vol. 6 No. 6 (2012): CUAJ December

Section

Original Research

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