Role of lymphadenectomy for invasive bladder cancer

Authors

  • Faysal A. Yafi Department of Surgery (Urology), McGill University, Montréal, QC
  • Wassim Kassouf Department of Surgery (Urology), McGill University, Montréal, QC

DOI:

https://doi.org/10.5489/cuaj.1197

Abstract

Radical cystectomy with lymph node dissection remains the standard
of care in the treatment of muscle-invasive and refractory
non-invasive bladder cancer. Over the past decade, the extent of
lymphadenectomy has varied to include dissection up to the common
iliac vessels and aortic bifurcation proximally (may also extend
up to the level of the inferior mesenteric artery), the genitofemoral
nerve laterally, the circumflex iliac vein and lymph node of Cloquet
distally, and the hypogastric vessels posteriorly (obturator fossa,
presciatic nodes bilaterally and the presacral lymph nodes over
the sacral promontory). Evidence supports the role of lymphadenectomy
as both a therapeutic and prognostic variable in patients
with invasive bladder cancer. We review the literature regarding
the role and extent of lymphadenectomy, as well as its impact on
patient outcomes.

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Author Biographies

Faysal A. Yafi, Department of Surgery (Urology), McGill University, Montréal, QC

Wassim Kassouf, Department of Surgery (Urology), McGill University, Montréal, QC

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How to Cite

Yafi, F. A., & Kassouf, W. (2013). Role of lymphadenectomy for invasive bladder cancer. Canadian Urological Association Journal, 3(6-S4), S206-S210. https://doi.org/10.5489/cuaj.1197