The optimal management of T1 high-grade bladder cancer

Authors

  • Kenneth G. Nepple University of Iowa Department of Urology, Iowa City, IA
  • Michael A. O’Donnell University of Iowa Department of Urology, Iowa City, IA

DOI:

https://doi.org/10.5489/cuaj.1194

Abstract

Stage T1Hg bladder cancer should be considered an aggressive and
potentially lethal disease. The importance of initial re-resection to
identify unrecognized muscle-invasive disease is significant. Most
patients with high-risk disease are candidates for initial bladder salvage
with intravesical bacillus Calmette-Guerin vaccine for
immunotherapy, a procedure with a high survival rate; however,
failure of the procedure may result in a guarded prognosis. Even
after apparent success, patients should be informed of the risks of
the disease progressing to muscle-invasive or metastatic disease
and the need for vigilant monitoring. Despite optimal management,
a significant number of patients relapse or progress to invasive disease
requiring cystectomy. This review provides insight into the
optimal management of T1 high-grade bladder cancer.

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Author Biographies

Kenneth G. Nepple, University of Iowa Department of Urology, Iowa City, IA

Michael A. O’Donnell, University of Iowa Department of Urology, Iowa City, IA

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How to Cite

Nepple, K. G., & O’Donnell, M. A. (2013). The optimal management of T1 high-grade bladder cancer. Canadian Urological Association Journal, 3(6-S4), S188-S192. https://doi.org/10.5489/cuaj.1194

Issue

Vol. 3 No. 6-S4 (2009): CUAJ December Suppl 4

Section

Review

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