Perfusion CT evaluation in experimentally induced testicular torsion

Authors

  • Gulgun Yilmaz Ovali Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey
  • Omer Yilmaz Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey
  • Serdar Tarhan Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey
  • Abdulkadir Genc Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey
  • Peyker Demireli Celal Bayar University, Medical Faculty, Department of Pathology, Manisa, Turkey
  • Ozum Tunçyurek Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey
  • Cansu Unden Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey
  • Can Taneli Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey
  • Yüksel Pabuscu Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey

DOI:

https://doi.org/10.5489/cuaj.1148

Abstract

Introduction: In this study, we define the characteristics of perfusion
computed tomography (CT) in an experimental model of testicular
torsion.

Methods: Twenty male Sprague-Dawley rats were included for
the study. Torsion was applied to 10 rats and perfusion CT was
performed in the first hour to evaluate the following perfusion
parameters: blood flow (BF), blood volume (BV) and time to peak
(TTP) values. Detorsion was done for the same rats, and perfusion
CT was repeated 2 hours later to evaluate reperfusion. Ten
rats were left as part of the control group.

Results: There is significant statistical correlation between the BF
and BV values in the torsion and control groups (p = 0.001 and
p = 0.001, respectively). There is no statistical correlation of the
TTP parameters between the groups. No correlation was found
between torsion and detorsion perfusion parameters.

Conclusion: Perfusion CT can demonstrate the testicular perfusion
insult in an experimental model of torsion. Perfusion CT may be
an alternative method for diagnosis of torsion in indeterminate
cases. Following detorsion an interval of 2 hours is not sufficient
for demonstrating luxury perfusion of the testis.

Introduction : Dans cette étude, nous définissons les caractéristiques
d’une tomodensitométrie (TDM) de perfusion dans un mo -
dèle expérimental de torsion testiculaire.

Méthodologie : Vingt rats Sprague-Dawley mâles ont été utilisés
pour l’étude. Une torsion a été appliquée chez 10 rats et une
TDM de perfusion a été effectuée dans l’heure suivante pour éva -
luer les paramètres suivants : débit sanguin (DS), volume sanguin
(VS) et temps nécessaire pour arriver aux valeurs maximales (TVM).
On a procédé à une détorsion chez les mêmes rats avant de répéter
la TDM de perfusion 2 heures plus tard. Les 10 autres rats formaient
le groupe témoin.

Résultats : Il existe une corrélation significative sur le plan statistique
entre les valeurs de DS et de VS dans le groupe ayant subi
la torsion et le groupe témoin (p = 0,001 et p = 0,001, respectivement).
Par contre, aucune corrélation statistique n’a été observée
dans les deux groupes concernant les valeurs de TVM, ni entre
les paramètres de perfusion liés à la torsion et la détorsion.

Conclusion : Une TDM de perfusion peut permettre de démontrer
une anomalie de perfusion testiculaire selon un modèle expérimental
de torsion. La TDM de perfusion peut constituer une mé -
thode diagnostique de rechange dans les cas indéterminés. Après
la détorsion, un intervalle de 2 heures ne suffit pas pour démontrer
une perfusion excessive des testicules.

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Author Biographies

Gulgun Yilmaz Ovali, Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey

Omer Yilmaz, Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey

Serdar Tarhan, Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey

Abdulkadir Genc, Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey

Peyker Demireli, Celal Bayar University, Medical Faculty, Department of Pathology, Manisa, Turkey

Ozum Tunçyurek, Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey

Cansu Unden, Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey

Can Taneli, Celal Bayar University, Medical Faculty, Department of Pediatric Surgery, Manisa, Turkey

Yüksel Pabuscu, Celal Bayar University, Medical Faculty, Department of Radiology, Manisa, Turkey

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How to Cite

Yilmaz Ovali, G., Yilmaz, O., Tarhan, S., Genc, A., Demireli, P., Tunçyurek, O., Unden, C., Taneli, C., & Pabuscu, Y. (2013). Perfusion CT evaluation in experimentally induced testicular torsion. Canadian Urological Association Journal, 3(5), 383–6. https://doi.org/10.5489/cuaj.1148

Issue

Vol. 3 No. 5 (2009): CUAJ October

Section

Original Research

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