Optical coherence tomography: a novel modality for scrotal imaging

Authors

  • Cole Davis Urologic Oncology Fellow, University of California, San Francisco, Calif.
  • Wayne Kuang Assistant Professor, University of New Mexico, One University of New Mexico, Albuquerque, NM

DOI:

https://doi.org/10.5489/cuaj.1128

Abstract

Background: For patients with nonobstructive azoospermia,
sperm retrieval rates remain modest. We describe the use of
optical coherence tomography to improve retrieval rates and to
decrease tissue destruction.

Methods: Four patients underwent diagnostic testicular biopsy
and imaging with the Niris optical coherence tomography de -
vice. We performed a descriptive comparison between optic al
coherence tomographic images and conventional histology.

Results: The measured seminiferous tubule diameter differed by
16 μm between comparative imaging from optical coherence
tomography and conventional histology using hematoxylin and
eosin staining.

Conclusion: We illustrate the usefulness of optical coherence
tomography in the setting of testicular biopsy and the management
of nonobstructive azoospermia.

Contexte : Chez les patients atteints d'azoospermie non obstructive,
les taux de collecte de spermatozoïdes demeurent modestes.
Nous décrivons le recours à une tomographie optique
cohérente pour améliorer les taux de collecte et réduire la
destruction tissulaire.

Méthodes : Quatre patients ont subi une biopsie testiculaire diagnostique
et une épreuve d'imagerie à l'aide d'un appareil Niris
de tomographie optique cohérente. Une comparaison descriptive
a été effectuée entre les images obtenues par tomographie
optique cohérente et les résultats des épreuves histologiques
standard.

Résultats : La différence dans le diamètre des tubules séminifères
mesuré par tomographie optique cohérente et par coloration histologique
à l'hématoxyline-éosine n'était que de 16 μm.

Conclusion : Nous présentons une étude descriptive illustrant l’uti -
lité de la tomographie optique cohérente pendant une biopsie
testiculaire en vue de la prise en charge d'une azoospermie non
obstructive.

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Author Biographies

Cole Davis, Urologic Oncology Fellow, University of California, San Francisco, Calif.

Wayne Kuang, Assistant Professor, University of New Mexico, One University of New Mexico, Albuquerque, NM

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How to Cite

Davis, C., & Kuang, W. (2013). Optical coherence tomography: a novel modality for scrotal imaging. Canadian Urological Association Journal, 3(4), 319–22. https://doi.org/10.5489/cuaj.1128

Issue

Vol. 3 No. 4 (2009): CUAJ August

Section

Original Research

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