Granular cell tumour of the ureter: first case reported
DOI:
https://doi.org/10.5489/cuaj.1051Abstract
A 33-year-old woman presented with nonspecific, colicky pain of
the left lower abdomen. Computed tomography (CT) revealed a
2-cm mass engulfing the mid–left ureter. Ureteroscopy and biopsy
revealed normal mucosa, and CT-guided biopsy of the mass
was nondiagnostic. The patient underwent laparoscopic exploration.
A frozen section taken from the mass revealed a granular
cell tumour. We excised the whole involved portion of the ureter
and performed end-to-end ureteroureteral anastamosis. The postoperative
course was uneventful. Examination of a segment of
resected ureter revealed a granular cell tumour diffusely infiltrating
the wall of the ureter. There were no features suggesting
a malignant phenotype. On follow-up, the patient was found to
have developed a stricture at the anastomotic area, which was
successfully treated with balloon dilatation. To our knowledge,
this is the first reported case of a granular cell tumour involving
the ureter.
Une patiente de 33 ans présente des douleurs non spécifiques
au quadrant inférieur gauche de l’abdomen rappelant des coliques.
Une TDM révèle une masse de 2 cm englobant la portion
centrale de l’uretère gauche. Une urétéroscopie et une biopsie
ne révèlent aucune anomalie de la muqueuse, et une biopsie
de la masse guidée par TDM n’a pas permis de poser un diagnostic.
La patiente a subi un examen par laparoscopie. Des fragments
congelés de la masse ont révélé une tumeur à cellules granuleuses.
Une excision de la partie atteinte de l’uretère a été suivie
d’une anastomose urétéro-urétérale. Aucune complication postopératoire
n’a été signalée. Le rapport final de pathologie fait
état d’une tumeur à cellules granuleuses s’étant infiltrée de façon
diffuse dans la paroi de l’uretère. Aucune observation ne porte
à croire à la présence d’un phénotype malin. Au suivi, la patiente
présentait une sténose de la région de l’anastomose qu’on a pu
traiter efficacement par dilatation par ballonnet. À notre connaissance,
il s’agit du premier cas de tumeur à cellules granuleuses
touchant l’uretère.
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