TY - JOUR AU - Crook, Juanita AU - Black, Peter C. AU - Spiess, Philippe E. AU - Pettaway, Curtis PY - 2022/01/27 Y2 - 2024/03/29 TI - The first International Penile Advanced Cancer Trial (InPACT) opens in Canada! : Why additional centers are needed JF - Canadian Urological Association Journal JA - CUAJ VL - 16 IS - 2 SE - CUAJ Spotlight DO - 10.5489/cuaj.7704 UR - https://cuaj.ca/index.php/journal/article/view/7704 SP - 70-1 AB - <p>Penile Cancer is rare in Canada and the Western world. For this reason, penile cancer lags well behind most other malignancies in the development of evidence-based guidelines for management. This dilemma was the basis for the international cooperation to develop InPACT: the International Penile Advanced Cancer TrialĀ  (NCT02305654), sponsored by both the National Cancer Institute (lead by ECOG-ACRIN Cooperative Group) and Cancer Research of the United Kingdom (CRUK). The aim of InPACT is to determine prospectively the potential benefits of chemotherapy or chemoradiation in addition to lymph node dissection in patients with clinical evidence of inguinal lymph node metastases. InPACT is now open in Canada. We will review the eligibility and randomizations.</p> ER -