Case: Spontaneous regression of post-radical prostatectomy prostate-specific antigen elevation without adjuvant therapy in a patient with lymph node metastasis

Authors

  • Taehyoung Lee McMaster University
  • Yanbo Guo McMaster University
  • Saahil Vij McMaster University
  • Rahul Bansal McMaster University
  • Nathan C. Wong McMaster University
  • Bobby Shayegan McMaster University

DOI:

https://doi.org/10.5489/cuaj.4324

Abstract

Prostate cancer remains the most frequently diagnosed cancer among men. The combination of clinical stage, serum prostatespecific antigen (PSA), and Gleason score (biopsy) assists in predictive assessment of pathological stage and prognosis. Furthermore, pathological criteria, including Gleason score, surgical margin status, extracapsular extension, seminal vesicle invasion, and lymph node involvement, provide prognostication in patients undergoing radical prostatectomy (RP). In this paper, we present a case of a patient with high-risk prostate cancer with persistent PSA elevation post-RP who experiences a complete regression of PSA without any adjuvant therapy. To the authors’ knowledge, such a finding has not been described in the literature previously.

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Published

2017-07-11

How to Cite

Lee, T., Guo, Y., Vij, S., Bansal, R., Wong, N. C., & Shayegan, B. (2017). Case: Spontaneous regression of post-radical prostatectomy prostate-specific antigen elevation without adjuvant therapy in a patient with lymph node metastasis. Canadian Urological Association Journal, 11(7), E315–7. https://doi.org/10.5489/cuaj.4324

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Residents' Room